The Laboratory of Pharmaceutical Microbiology (LPM) of Ghent University aims to carry out basic and applied research in the field of sociomicrobiology, i.e. research on the group behaviour of micro-organisms. More specifically, research is centered around biofilm formation by various micro-organisms grown as single cultures or multispecies communities, the evaluation of novel strategies to prevent biofilm formation and/or eradicate existing biofilms, and the molecular basis of tolerance and resistance in biofilms. The LPM also has an interest in host-microbe interactions and explores host- and microbiota directed approaches to treat bacterial infections and detrimental processes in the host due to the infection (e.g., inflammation).
Missed us at a conference?
Have a look at these past talks/abstracts
Interview with Prof. Tom Coenye for the honorary doctorate of Prof. John LiPuma
Epigenetic control of social behavio
DNA Methylation Epigenetically Regulates Gene Expression in Burkholderia cenocepacia and Controls Biofilm Formation, Cell Aggregation, and Motility July 23, 2020
Small RNAs in Burkholderia metabolism.
Low iron-induced small RNA BrrF regulates central metabolism and oxidative stress responses in Burkholderia cenocepacia July 23, 2020
Congratulations Dr. Wille!
PhD thesis on biofilm dispersal - March 31, 2020.
treatment of multispecies biofilms
Antibiotic susceptibility of cystic fibrosis lung microbiome members in a multispecies biofilm – June 13, 2020.
Grant awarded to Tom Coenye
o Concerted Research Action grant on identification of adaptive mechanisms leading to reduced antibiotic susceptibility in bacterial biofilms using experimental evolution and machine learning approaches – October 2019
Small RNAs in Burkholderia metabolism
Small RNA NcS27 Co-Regulates Utilization of Carbon Sources in Burkholderia cenocepacia J2315 – October 1, 2019.
ESCMID research grant for A Crabbé
Study on the influence of host metabolites on antibiotic activity – April 1, 2020
Metabolism and antibiotic tolerance
Review article on how metabolic adaptation in microbial biofilms influences tolerance to antibiotics - June 6, 2019.
Best paper award for Rosalie!
Rosalie Swimberghe received the prestigious Wladimir Adlivankine Research Prize from the European Society for Endodontology for her work on endodontic biofilm models - September 12, 2019
Congratulations Dr. Eline Teirlinck!
PhD thesis on using vapor nanobubbles to treat biofilms (Laboratory for General Biochemistry and Physical Pharmacy (Prof. K Braeckmans) and Laboratory of Pharmaceutical Microbiology (Prof. T Coenye)). June 24, 2019. Click on the link below to discover her work.
Lung cells influence antibiotics
Publication on how 3-D lung epithelial cells enhance the activity of aminoglycoside antibiotics - April 29, 2019
Congratulations Dr. Vandeplassche!
PhD thesis on antibiotic efficacy in multispecies biofilms - November 21, 2018. Discover Eva Vandeplassche's work below.